Oprah's Done with the Shame. The New Weight Loss Drugs.

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Oprah Winfrey shows off her most recent weight loss at World Premiere of Warner Bros.' "The Color Purple" earlier this month. Leon Bennett/Getty Images hide caption

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Leon Bennett/Getty Images

Oprah Winfrey shows off her most recent weight loss at World Premiere of Warner Bros.' "The Color Purple" earlier this month.

Leon Bennett/Getty Images

Americans are increasingly using drugs like Ozempic, Wegovy and Mounjaro to lose weight. And they got a big endorsement last week when Oprah Winfrey announced that she, too was using weight loss drugs.

And it's not just Oprah, the decades-old weight management company Weight Watchers is also embracing the drugs, integrating them into the business model.

NPR's Juana Summers speaks with Weight Watchers CEO Sima Sistani about the company's decision, and talks to NPR consumer health correspondent Yuki Noguchi about what is known and unknown about these drugs.

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The episode was produced by Avery Keatley, Connor Donevan and Alejandra Marquez Janse. It was edited by Tinbete Ermyas, Scott Hensley and Courtney Dorning.

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